NCRI Research: Better Diagnosis, Prevention, Treatment

We understand how devastating cognitive impairment can be. Neurological disorders are the leading cause of death and disability in the world today with about 1 in 7 people suffering from neurological disorders. These disorders severely disrupt lives and often lead to premature death. It is our responsibility to our contributors to conduct our research studies meticulously, thereby making the entire process and goals easily understood. We want you, the consumer, to know what our studies are about.

 Upcoming Research Projects

qEEG/swLORETA Brain Sensitization Pilot Study

Central sensitization refers to a brain state whereby neurons become dysregulated, resulting in signs of hypersensitivity to both noxious and nonnoxious triggers. This pilot study is meant for patients with one or more of the following diagnoses: Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS), Fibromyalgia, Migraine Syndrome, and Dysautonomia. qEEG/swLORETA methods with 3-dimensional neuroimaging are used to evaluate the nature and extent of neurological symptoms patients. The primary aims of the study are 1) to assess the neuropsychological status of the participants, 2) linkage of symptoms and behavior to functional brain connectivity using qEEG/swLORETA. This results will provide valuable clinical information for differentiating these conditions for improving understanding and guiding practitioners in assessing clinical outcomes for the phenomenon of central sensitization. There is no compensation, but participants get to see their brain activity in real time compared to an age-adjusted normative QEEG database.

The slideshow below shows examples of significant brain network dysregulation in a patient with ME/CFS


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